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KMID : 0988920090070020123
Intestinal Research
2009 Volume.7 No. 2 p.123 ~ p.128
A Case of Gastrointestinal Amyloidosis in Asymptomatic Multiple Myeloma
Kim Sae-Hee

Lee Yun-Jung
Jung Sung-Hee
Hyeon Woo-Jin
Lee Hyang-Ie
Yang Hyeon-Woong
Kim An-Na
Cha Sang-Woo
Kang Dong-Wook
Abstract
Amyloidosis is a disorder characterized by extracellular deposition of amyloid materials in multiple organs and tissues. Amyloidosis commonly shows a systemic involvement. Gastrointestinal involvement is common in amyloidosis and is usually asymptomatic. The gastrointestinal manifestations include gastroparesis, diarrhea, steatorrhea, constipation, intestinal pseudo-obstruction, and bleeding. The diagnosis of amyloidosis is difficult because there are absence of systemic symptoms and nonspecific endoscopic findings. Asymptomatic multiple myeloma is an asymptomatic plasma-cell proliferative disorder associated with a high risk of progression to symptomatic multiple myeloma or amyloidosis. Recently, we experienced a 60-year-old man who presented with hematochezia and weight loss as manifestations of gastrointestinal amyloidosis involving the stomach and the colon induced in asymptomatic multiple myeloma confirmed by endoscopic biopsies and bone marrow biopsy. We report a case with a review of the literature.
KEYWORD
Amyloidosis, Multiple Myeloma, Stomach, Colon
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